I am 56 years old and was on Advair for about a month and found that I was having night time leg cramps. I have always had occasional problems with night time leg cramps, but the Advair was causing cramps every night. Many nights I was having several episodes which would cause me to get out of bed and walk off the cramp. One night I counted about six times that I got up with very painful cramps. So I stopped the Advair and now I am sleeping again. I think it will take a while before I feel rested again. I am so tired from this whole experience. Leg cramps are not listed as a major side effect for Advair, but it should be. These leg cramps were agonizingly painful.