I started the NuvaRing three weeks ago and I took it out on Thursday so I can start my period. For the last few days I have been depressed, moody and ready to punch anyone that looks at me the wrong way. I am very active and usually always smiling I feel like it's painful to even try and crack a smile now. I am having a very hard time concentrating even if it's just a phone conversation. I didn't think it was from the NuvaRing until I found this site. I will probably discontinue use.