I was prescribed this for Epididymitis (sp?) about 4 weeks ago (100mg 2x a day). After a week or so on the meds, I began to have a striking number of the symptoms that everyone else has listed previously: Chest/Ab cramping, feelings of swelling in random places, loss of appetite, dramatic mood swings, a high level of anxiety, crying for no reason, confusion and panic attacks...I called my GP today for a psych referral, and when he calls me back I'm going to ask to be taken off the Doxy. Thanks to everyone who posted, it helped me for sure!