I was prescribed the wellbutrin for anger related to quitting smoking, took it for 10 days with no problem, then BAM.. huge hives all over my body. Broke out on Saturday, Sunday they were worse, Monday it looked like i had Chemical burns over 60 percent of my body. Went to the doctor, was prescribed steroids, zantac, and ataban. within 6 hours of taking the steroids, hives were down, it is now Tuesday, 3 days after first outbreak, my skin is still pink where the hives were. Apparently we are in the 6 percentile that get hives with wellbutrin.