I have been on Toprol XL or the generic for over seven years. After the first two months on it I started to notice small, scaly patches appearing on my hands and arms. I was told this was just a coincidence. I had the areas biopsied and was told it was Granuloma Annular. Whatever?? Apparently there is no cure. I have never had any skin problems in my life and I,m sixty seven years old. I also noticed I,m constantly fatigued, cough constantly, still have heart palpitations and seldom get a good nights sleep. I,ve tried to get the doctor to discontinue it or put me on something else and they all act like they are afraid to try it. I,ve been tested and was told my PVC,s are benign, so why the concern? I just want to get off this stuff.