I am a 27 year old female and have suffered from migraines for 10 years. My neurologist prescribed 12.5 mg for the 1st week, 25 mg the 2nd week, 37.5 mg the 3rd week and 50 mg by the 4th week and then we will re-evaluate on the 6th week. I am on my 2nd day and have experienced a few side effects.....tingling in my arm and lips, frequent diarrhea, carbonated drinks taste flat, trouble typing/spelling and a burning sensation in my eyes. My arm also feels heavy and dead. I am willing to give topamax a try--I can't stand living with my migraines! I think the most bothersome side effect is the inability to type/spell correctly. Hopefully with time, these effects will subside. Wish me luck! (hope I spelled everything correctly!)