I had the mirena inserted about a year and a half ago. Since then I have gained 20 pounds. I have never had to fight weight gain. I'v been a stable 130 for probably 10 years. Never had to worry about what I ate or when I ate. Now, I'm eating salad, low fat stuff, fat free stuff and exercising. Of course that's all good for me, but, if I hadn't gained the 20 pounds, I would never have to eat this stuff. I've been meeting with a dietician and everything. It's been 4 1/2 weeks and I haven't lost a pound. My GYN is going to do lab tests tomorrow to see if it's my hormones, or maybe perimenopausal. I'm 46 years old with 3 kids. If the tests come back negative, I'm going to have it taken out. Hopefully I'll be able to loose this 20 pounds. I feel huge. Other than that, I have had no problems with it. The insert process was a little painful, spotting for a few months, but nothing else. Good luck with the rest of you.