My Lupron experience has been mixed.
I had 3 Lupron injections--7 months worth of the drug--before my November 2003 myomectomy for a grapefruit-sized fibroid. I consulted 4 doctors (including a family member) before taking the Lupron plunge, and opted not to read too many scare stories online. I'm 32 and I want very much to have children, and everyone told me that my surgery would be most effective if we could use Lupron to cut the blood flow to the fibroid. The good news is that it seems Lupron (and a very good surgeon) did the trick--my surgery was without complications and declared a success. (Now we just have to get me pregnant!)
Now I'm just waiting for the effects of Lupron to go away. I had my last (3 month dose) shot in September 2003, and my most severe symptoms were in the weeks after that shot--especially severe and frequent hot flashes, night sweats, the works. For the entirety of the injection, my libido was utterly shot. For me, these were all annoying, but not unbearable. I figure it's just a taste of what's to come when the real menopause happens in another decade or so.
Post-Lupron recovery:
The hot flashes finally went away about 5.5 months after my last shot, and I've been gradually feeling more and more normal, though my libido is still not back to normal. Most worryingly, and this is why I'm writing today, is what happened to me this last week. Noone ever seems to write about the hormonal hell that your body goes through when it's trying to return to it's pre-menopausal state. I'm 90% sure that my symptoms are in fact attributable to these hormonal fluxes, and not to something worse (like abdominal adhesions from my surgery).
Three evenings ago, I got extremely dizzy and nearly passed out. It took me over 20 minutes to get back to my office, since I was so dizzy (loss of vision, balance, and nauseaI had to sit down three times in the couple dozen yards. I also had a pain in my abdomen. I barely made it the final steps to my office, where it took me at least 45 mintues to get to the point where I could make it to the car to go home. I had strong stomach pain, tingling hands, and gradually decreasing dizzyness. At this time I also noticed that my entire abdomen was very swollen. While the other symptoms have not returned, I have continued to have a very swollen abdomen, which has been very tender to the touch. I have been unable to walk at my usual vigorous pace, and have spent much of the last 3.5 days sitting quietly or lying down. The whole experience has been very frightening--and NOTHING like any PMS I have ever had before. But then again, I've never been menopausal for a year before!
So, I'm writing this post so that others might be aware that the hormonal changes the body goes through while getting OFF Lupron can be even more severe and frightening than the ones you experience going ON the drug.