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Has anyone been in contact with any doctors, hospitals, or resear...

Posted at 10:41 AM on May 06, 2009 by concernedcitizen, #41247
Has anyone been in contact with any doctors, hospitals, or researchers who are willing to recognize that Singulair targets a receptor CysLT1, with known genetic variations? As you know, I have been posting that I know of researchers who are doing work about how the genetic variations can determine the efficacy of Singulair. If genetic variations cause differences in efficacy, then, of course, these variations can also cause unpleasant to very serious side effects. These seems to be some kind of disconnect. How can the genetic component be recognized in the area of efficacy and ignored in the area of adverse drug reactions?
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Reply 6 months ago on May 06, 2009 by massmomof3, #19564

Wouldn't it be great if some researcher took this on - I think there is tremendous potential to learn about how and why the brain reacts differently to drugs. Also, perhaps this research could lead to a better understanding of problems such as anxiety and suicidal ideation that crop up as side effects from drugs, but also arise from unknown reasons - reactions to stress combined with genetic tendencies.

I myself don't know how to find researchers to take this on - I suppose much of the research funding comes from pharmaceutical companies, but some comes from philanthropic or government institutions. Keep us posted if you find anyone interested.

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Reply 6 months ago on May 06, 2009 by kate2, #19565

Hey it good to see you back on this board!!!!!!
I for one, wish the FDA would call for new clinical trials on Singulair and use the Columbia University method to look at psychological side effects.There are way to many drugs that get approval on the fast track and these side effects pop up.To Bad the investigation into the problems does not go as fast as the approval process.I wish that you had someone in research to refer us to,I would be more than willing to contact the Pope to get this thing taken seriously!Again welcome back,Kate

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