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I started taking Lisinopril for high blood pressure and 3 weeks a...

Posted at 5: 6 PM on May 11, 2009 by tmccarty, #41389
I started taking Lisinopril for high blood pressure and 3 weeks after developed urinary tract symptoms (frequency, pressure, some discomfort, itching). The first time I went to the gynecologist to leave a urine sample, they prescribed me antibiotics, which I took for 7 days and still the symptoms continued (my urine had tested negative), so I went back and gave them another urine sample, it tested negative again, but had blood in it. They gave me a higher dose antibiotic for 3 days, the symptoms were still there. After that, there was nothing they could do, so they sent me to a Urologist. By the time I got in to see the Urologist, a month and a half had gone by and I decide to quit taking the Lisinopril to clear my body of anything. I ended up getting a kidney scan, which was normal... and then a urinary tract scope procedure, which was normal. After these procedures, I noticed that I started getting better and thought I might have just had "Acute urethral syndrome (also called noninfectious cystitis) causes symptoms that are similar to those of a bladder infection but that continue for longer periods. It is not an infection. No bacteria or other microorganisms are in the urine. The cause of acute urethral syndrome is difficult to determine. Possible causes include injury or irritation, allergies, stress, a disorder of the nerves, or problems with the immune system. You may be able to relieve symptoms of acute urethral syndrome by avoiding bubble baths and other irritants and not drinking citrus juices and caffeinated fluids." So, I went back on Lisinopril, which was a few weeks after I quit taking it. After only 3 days, I started getting the frequency, discomfort and some itching... I could only figure out that Lisinopril had everything to do with my symptoms. This is still to be determined, but I feel like my urinary tract is feeling better every day now.
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Reply 6 months ago on May 11, 2009 by roscoemonkey, #19728

Good thing you got off of it. It about killed me. I had isolated visceral angioedema and it sounds like you may have been experiencing the same. Extremely rare side effect. Dr. never did figure it out even after all of the test since they all came back negative. I had to do the research and figure it out on my own. Cost me $3K. This went on for 2 months even after I kept asking Dr. if it could be the Lisinopril. I was in severe pain every day. Quit taking it and got better.

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