I have taken two Pletal as directed..one last evening on an empty stomach and one this morning on an empty stomach. This afternoon "Suddenly" I was HIT with diarrhea out in public..NO warning. Again and again before I could get home to change clothes..and then a headache. I have a painful, swollen stomach, headache and will not be taking anymore pletal for my sjogrens symptoms (cold, numb hands and feet).