I guess this is case and point that all medications does not affect everyone the same! I took 8 Lupron shots and never gained a pound (lost some in fact, from all the sweating), never got headaches and my sex drive was unbelievably WAY up there!! I looked forward to each shot. The only side affect I considered unbearable was the hot flashes. I coped and again, I lost weight; therefore, I considered it a great sacrifice. I had a wonderful experience. After my first shot, I did get very emotional, but after the second one, I was enjoying the benefits. My energy level was up and I seemed to have had a new zest for life. It seems that every side effect mentioned by both my doctor and research was the opposite for me. My recommendation for anyone looking into the shots is to try it and see how it affects YOU instead of letting bad experiences by others guide you. Good Luck Ladies!