Yes it does affect your kidneys, you are on a really high dose too, I think the maximum is meant to be 400mg a day. For everyone that says their doctors are telling them that their symptoms are not side effects from Lamictal, all you have to do is take in the information leaflet (the tiny folded up paper one) that comes in the box with the pills. Some companies have less side effects listed in their leaflet which is odd (GlaxoSmithKline hardly lists any) But APS lists involuntary movement of the eyes. There was another brand I used to be on that had a huge long list of side effects but I can't think what it was. If you search online you should be able to find a good list.