I had Mirena put in three months ago after my doctor told me the hormones would not enter my bloodstream (I am very sensitive to hormones and reacted adversely to traditional birth control pills). I didn't notice the side effects immediately but they have progressively become worse over time. My side effects include bouts of constipation (2-3 days) followed by diarrhea, nausea, frequent (1 a month) vaginal yeast infections, abnormal vaginal ph (causes a terrible odor), pain in my abdomen so extreme that I landed in the emergency room once, irritability, depression, weight gain, thinning hair and acne like I've never had. My fiancee thinks I'm making all of this up but I am absolutely convinced it is caused by the Mirena. I'm having it taken out this week and will be back to share whether it has alleviated my symptoms.