I was on Advair for a few months back in about 2005. I was taking it for asthma. I noticed after about a month of using it that I would have these severe asthma attacks if I came in contact with an irritant. Instead of minor coughing if I was near someone smoking my lungs would practically slam shut and I could not get any air. These were far more reactive and severe than I have had on any other meds or none at all. I stopped taking it, switched back to Flovent and the problem went away. A few months later the FDA announced the black box warning for Advair and that this was a possible severe side effect. They need to be more up front with patients about this risk so they can decide if it is worth using, I wasn't given that option.