I have only been taking Jolessa for two weeks and already feel so depressed. I have always been a happy person and now getting out of bed sometimes is difficult. I have to force myself to laugh at jokes and nothing seems to cheer me up. I also feel anxious a lot. I cant say that I am certain it is because of the pill, however, there have been no other changes in my lifestyle or diet. I have experienced no other side effects and will continue taking it until I run out.