Provigil saved my life! Been taking it every day for years now after a weird sleep condition left me virtually bed bound, unable to work-it was thought I had Chronic Fatigue Syndrome, until I was sent to a sleep clinic! The first couple weeks taking provigil I had indigestion type symptoms, so just avoided taking on an empty stomach. Also every few months it seems to become less effective, so I just schedule in a 1-2 break. Otherwise, its great!