I had the Mirena inserted December 2007 and I thought everything was going great! Then the weight gain started it was like I gained weight in my sleep I went from a size 14 to a 20 and I hate it. My hair stopped growing and started shedding really bad. My face looks blotchy and rough and I've developed a skin rash that itches terribly. I'm irritable as HELL and my sex drive is completely gone. I hadn't had a period since I had the Mirena placed and three weeks ago I started cramping really bad I felt like I was in labor, I couldn't walk or stand up straight. I took some Advil laid down and woke up in a puddle of blood, by the time I could get to the bathroom I had started passing large blood clots. I went to the hospital and they did nothing gave me a prescription for Vicodin and Codeine. As of today I'm still having the same complications with no sign of getting better. Thanks to all the ladies and their post I now know that Mirena is the root of this evil. Thank you to everyone and hope you all find relief because I just called to have this thing removed first thing in the morning!!!!!