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I just went in for my second shot of Lupron (out of a series of 6...

Posted at 6:16 PM on May 28, 2009 by thylacine0113, #41842
I just went in for my second shot of Lupron (out of a series of 6) for treatment of stage IV endometriosis. The most noticeable side effect I experienced was during my first menstrual cycle after my first dose of Lupron. I had never experienced menstrual pain or cramping (even though I had advanced endometriosis) until after Lupron. I have a fairly high pain tolerance and yet the cramping for the first 2 days of my period were almost debilitating. I had extremely heavy bleeding and have had spotting daily ever since (app.18 days). I have gained about 3 pounds because I have no energy at all. I'm usually active and work out 4-5 times a week but by the time I get off work, I'm too fatigued to do so (hence the weight gain I guess). I have hot flashes and night sweats all the time. The most recent side effect is high blood pressure. I have never had high blood pressure in my life (I'm a healthy 25-year-old woman) and when I went in for my 2nd Lupron shot today, they told me I all of a sudden do. I don't seem to have mood swings but do feel depressed and sometimes more anxious than normal. I have experienced a decreased interest in sex as well.
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Reply 5 months ago on May 31, 2009 by haku, #20249

I was diagnosis with Endo last year, and had gone under surgery to remove the tissues and emptied one of my ovaries. After the surgery, my ob-gyn doctor told me that I am going to be treated with Lupron for six months, 3.75mg short, once a month.

I had no problem with the first short, however after I got my second shorts, two or three weeks after, I started to experience the menopause alike. Not only that, I also developed a severe side effects i.e. having migraine at least three times a week, joins pain, lost of memory, nervousness and heart palpitation while I was asleep. However, I did continue and had my third shorts, but I woke up the next morning and found myself cannot get out of the bed because the severe pain at joins area. I CANNOT walk for almost a week, and that was the last shorts of the Lupron for me (I called it off; by the way, I am a healthy and very active women, 29 yrs old).

It has been about four months now since I had my last short. It took me about two or three months after the last one to get completely over the side effects.

Now, I started to feel that the Endo has coming back again (severe pain on the lover right pelvic, frequently urinate). I am going back to see my ob-gyn next Friday.

I would never suggest anyone to use the Lupron as a treatment for Endo. It’s side effects are very nasty.

Samantha
Houston, Texas.

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Reply 2 months ago on Sep 05, 2009 by suztheq, #22760

I am 28 and just had surgery for endometriosis in July of this year, much to no avail. I still have extremely erratic bleeding and terrible pelvic pain. My doctor just recommended Lupron for me for at least six months -maybe longer. I think I'm the only woman in the world that doesn't care about my fertility. I have never wanted kids and as I get older, my opinion on this has gotten stronger. So that's taken care of. I trust my doctor since he has been so helpful and dead-on with my symptoms thus far. I feel like he actually listens to me. However, everything I have read about Lupron (including these two posts) has completely changed my mind. Luckily, my insurance company is dragging it's feet with this or I would have started it already. Has anyone ever had any luck with Lupron?! How on Earth did the FDA ever approve this medication for endo treatment. Thank you so very much for sharing your experiences. They are eye opening. My heart is with you ladies and I hope we can all find some relief from this horrible disease while keeping our goals (children or not) and our health in mind.

Suzie
Cincinnati, OH

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