Began taking Biaxin 500mg 1x a day recently for acne...have had a history in the past of migraines, but couldn't figure out why all of a sudden I was getting migraines EVERY day. I also had some stomach problems, but knew from looking up side effects that this was to be expected - but couldn't find anything about headaches/migraines being a side effect. I had also noticed that things weren't tasting quiet right, most especially my diet Pepsi, but couldn't figure out how that was a side effect - but am guessing that is the "abnormal taste" other's have described. I have called my doctor to asked about changing prescriptions, because I don't think I can handle a month of daily migraines - just to deal with acne!