I am 47 year old female with 5 days of headache and high diastolic bp. Doctor prescribed lisinopril. It made me want to sit for hours without moving. I was sleepy but could not sleep, cloudy thinking, anxious, thought I was going to die, had pangs all over my body and in extremities, racing heart with difficulty catching breath, etc to all the above symptoms. I stopped it after two weeks. I had bronchitis for four weeks. Then I developed dizziness/nausea and burning in the hands and feet. After researching that, I took a B12 and that tingling symptom cleared in a few hours. I don't know if the drug changes the metabolism in your system. I still am fatigued, occasionally have racing heart, and problems with sleep. Don't know how long it may linger in the system. Can't seem to find an answer. It has been 2 months since I took it and 6 weeks since being off it. By the way, my BP is now typically 117/82 with loss of 15 pounds. I prefer to treat naturally. Look up Taurine, CoQ10 and Hawthorne and see which may be best for you.