I have had my mirena for 3 1/2 years. I also have had a lot of hair loss, dry bloodshot eyes, migraines, anxiety and mood swings. Also you say a sense of detachment. That's exactly what I have experienced. I feel like I'm more withdrawn from people than I've ever been, and I have trouble enjoying life. I feel like I'm going through the motions every day but not really living. It's a very strange feeling and I'm really starting to think a lot of this is caused by Mirena.