I have a central disc bulge in lowest back I have tried many many types of medicines Tramadol worked and at first I felt a pinched feeling in the center of my skull I told my doctor and we gave time to adjust to medicine. Shortly after I started sweating heavily and I used it still as I was able to sit and stand and had greater mobility. I then started to get shaky alot and confused finally my groin started hurting and about a week later went numb my doctor then put me back on hydrocodone . Eat before use to avoid heavy nausea.