I am a 48 year old woman, 5'1" (now 145 pounds). I had Mirena ins...

I am a 48 year old woman, 5'1" (now 145 pounds). I had Mirena inserted almost exactly 5 years ago, and am scheduled to have it removed in 2 weeks. I gained 25 pounds over the course of the last three years; prior to that, my maximum weight for my whole (non pregnant) life was 123 (I was at 120 when Mirena was inserted, four years after the birth of my second child). I have always been very healthy, never abnormal blood tests except during my two pregnancies was tested as pre-gestational diabetic and had to watch my carbs. I never put it together with Mirena until just recently, when I started doing research on hypothyroidism after a friend told me that my symptoms could be due to that problem. Depression, hair loss, acne on my back, and the terrible weight gain. I went to see my G.P. who referred me for blood work. I hoped to see evidence of low thyroid function (actual TSH value, 3.12 -- I was told this is normal on a range of .4 to 4.5). I also discovered that I now have high cholesterol (269 triglycerides, 251 total cholesterol, 46 HDL, and 151 LDL). My fasting (14 hours) glucose # is 99 (I was told this is normal on a range of 65-99 mg/dL), and my vitamin D, 25-OH is 21 (also was told this is still normal but low on a range of 20-100 ng/mL). I tried to give blood six months ago, and was turned down because of anemia, so I've been eating a lot of spinach, greens, and more red meat than I normally would, so I was interested to see if I am still anemic -- the red blood cell count is 3.8 (told it was normal on a range of 3.8-5.1 mill/uL). I mention these specific results because although I was told they were normal (except for cholesterol), when I physically went to the doctor's office and requested a copy of the results and did some research online I see that my thyroid IS actually low-functioning -- according to guidelines revised six years ago, anything over 3.0 is considered hypothyroid and should be treated. Plus, isn't a fasting glucose of 99 pretty high? Yet my doctor's only suggestion: diet and exercise. Good grief, I've been on a diet since I had my first child, 13 years ago. True, I don't exercise regularly (I'm a teacher and mom of 2; I never seem to have the me time.) I guess I have an excuse to get a gym membership now. Also, for the last year I've had increasing pain in my shoulder (I couldn't lay on my side, for example, and lately I can't reach behind me or over my head). An x-ray turned up mild bone degeneration, but not enough to cause the pain I've been having. I was referred to an orthopedist, who today diagnosed a shoulder rotator cuff injury (I've had no injury; he says it is a common degenerative complaint in the over-40 crowd). He gave me a cortisone injection and I'll be on PT for a while to see if the pain goes away. If not, I'll have to have an MRI and surgery to correct the tear. I'm posting all of this in case it might be useful to someone out there who might be going through the same thing. I had a thyroid test done about six years ago at my OB/GYN, and it was normal then (though I don't have the number; I'll get it in 2 weeks at the OB/GYN). It will be interesting to learn whether my thyroid level has gone up since Mirena. Also, although my research suggests that the effects of these synthetic hormones do not wear off for some time, possibly even years, I will finally feel like there may be hope if my symptoms improve over the next few months when Mirena is gone. If so, I will share it with you. If you are reading this, perhaps you have a similar story. I wish I had been more aggressive about checking out the possible causes of my many symptoms, but I let them go for years because, I guess, I just figured I'm a healthy woman who is no longer young. (Oh, one more thing: for the first year or even two years that I had Mirena, I had incredibly heavy periods. The blood flow was similar to that during the day or two after the vaginal births of my daughters. Don't know if that's significant, but it took a couple of years for my periods to get fairly normal on Mirena.)