started taking seoquel 25 mg an hour before sleep, then 50 mg. went up to 75mg because i wasn't "tired" enough to sleep. it was working okay, but my friends had warned me that i might experience weight gain and absolutely uncontrollable hunger for carbs and sweets. and as a 46 yo woman that already weighed 200 lbs. that was not a happy prospect. but i ignored that; maybe it would be different for me. btw, i am diagnosed as bipolar 2 and am taking lamotrigine, celexa, lithium and now seroquel. i was in a couple months ago for anxiety and loss of time, for lack of a better term. my pdoc told be to get off the 75mg of benadryl i was taking and gave me samples of seroquel to help me sleep, etc.. so, after experiencing weight gain, sore breasts, bigger stomach (i don't have a scale), labored breathing when walking to the freakin' mailbox and feeling like a truck has run over me for at least half the day, then anxiety immediately following, i have decided to pitch the seroquel. also, i am going off lithium and my blood pressure med (i was taking that for migraines associated with pre menstruation and now am menopausal). i'm going to start melatonin again (which i used for years and it worked) when i'm weaned off the evil seroquel... sigh. and no, the docs DO NOT CARE ABOUT YOUR WEIGHT GAIN!!!! THEY JUST WANT TO KEEP YOU ALIVE AND UPRIGHT IF POSSIBLE! i'm more depressed knowing i could easily balloon upwards to god-knows-what. so if your doc hands you "free" samples of seroquel, please keep track of your symptoms. maybe it will work for you but be cautious, please!