I've been on doxy for about 10 days. I've never had problems with "photosensitivty" when it had been listed as a side effect on other medications. Totally disregarded the warning. I was put on it for some problems that might arise with acne due to a hormonal injection. I was going to the Florida keys in a few days and thought I should go to a tanning bed to get a little color so I wouldn't burn down in the Keys. Within a couple of days my hands began to tingle, burn with warm water, freeze with cool water. It was like my skin was burnt off and my nerve endings were exposed to the elements. While in Florida with my feet and hands in bandages to keep the heat/sun from causing pain I noticed blistering and still have them. I thought I had shingles, even though I had it on both sides of my body! Had an increased heart rate and 2t pitting edema in my feet and calves when flying home and increased itching on feet and hands. Very nervous at this point! I massaged my calves to increase the flow back towards my heart and it seemed to help. I am also experiencing GiI problems as well, severe heartburn and bloating. My son said I looked like I was pregnant! I can't wait to talk to my Dr. tomorrow and will stop taking this medicine. Thanks to all of you for your information. I'm relieved to find out what is causing all of this. I only hope my symptoms will go away sooner than later!