I have severe endometriosis & a double uterus(yes, that means 2 separate periods). My periods would last between 7 & 15 days w/ heavy clotting & very painful cramps. Last year my dr. said he didn't think it was good to bleed every month, so he put me on Jolessa. The 1st month was great w/ no period & no side effects. Then I started spotting & had a period on & off for about 2 months. Then, I didn't have my period for 2 months @ all & the following month had a 3 day period. The next month(May), I started spotting & it continued until 2 weeks ago(2nd week of July). Then an actual period started & is still continuing. So that's 7 weeks of spotting & 2 weeks(so far) of full bleeding. Besides the on/ off bleeding, I have had no other side effects. Although this severely irregular bleeding is annoying, it is still better than my regular periods so I am reluctant to stop taking them. My dr. said it could really take up to a year to fully regulate my cycle, so I am willing to wait.