i have been off Januvia for about 2.5 months. the joint problems I used to have seemed to have been gone. I am more alert now that I am not taking the drug. I am still having stomach problems big time. I hope they go away but don't seem to be wanting to go away. My stomach problems are so bad that my blood pressure shoots up very high 2 hours after eating and I feel my food is stuck right below the rib cage. I still get headaches. So beware that if you are stopping this medicine it seems that the side effects linger after a while. I took the drug for about 6 months