I love It! I have been experiencing low back pain when standing for over a year. I could hardly walk when I crawled out of the bed in the mornings. I was diagnosed with one point away from osteoporosis. The supportive tissue between my discs was deteriorating. I was given Evista to drive the calcium into the bone along with Limbrel 500 mg twice a day for the arthritic pain. My nails have become stronger which to me indicates my muscular structure must be getting stronger. I took Naproxen and Arthrotec previously to Limbrel and experienced severe stomach distress. I am 65 and I see a daily improvement from my previous condition. I have never experienced fever or chills. I am almost totally pain free and look forward to the future continuing to take Limbrel!