today is my first day off doxycycline. i was prescribed 100mg twice a day for 14 days for lyme disease which it got rid of. i already had some nausea and fatigue from the lyme , but this drug is wicked. while taking the drug i have had heartburn even with the glass of water, extreme nausea( lost 6 pounds in a week and a half) having to force myself to eat, depression with spells of wanting to cry and not wanting to go out and be active or talk to anyone which is unusual for me, and no appetite at all , seeing this site is a big relief for me , but how long does it take to make these side effects go away ( that the doctor says rarely happen) and any suggestions for helping them go away?