I am a 50 yr. old female diagnosed with diabetes 10 months ago. Tried Metformin for a couple of weeks and feet started swelling significantly. Have been on Januvia and Starlix since March '09. Just spent 9 days in the hospital with PNEUMONIA in my right lung only. Drs. are considering the fact that I have a very ENLARGED LIVER (19 cm. avg. is 12 cm) to be the cause of my pneumonia and having 3 liters of fluid removed from right lung cavity as the cause for my pneumonia. Liver function tests show liver is working fine. Anyone else have enlarged liver problems or pneumonia while on Januvia? I'm off it now and dreading what will happen to my sugar level. I also take ENBREL for my psoriatic arthritis and stopped it when my pneumonia developed.