My doctor switched me from Ortho cyclen to Ogestrel 28 for suspected endometriosis. I've only been taking it for four days. The most annoying side effects thus far have been the bloated, nauseous feeling, which is similar to what I experienced when I started on Ortho cyclen 12 years ago, though I can't recall if it was quite as intense as what I've been experiencing with Orgestrel.