I have been on Percocet 10/325 for 2 weeks now but i feel like they do not help at all I have been on Lortab 10/500 for over 5years they stopped working so my doctor put me on these I have had 7 back surgery thyroid removed because of cancer also have to have surgery on toes in about a week the only thing this med does is I feel nausea all day almost to the point of throwing up but I do not feel any pain relief