I got Mirena inserted in Oct 2007. A few months after getting the IUD put in, I started experiencing a lot of different things, such as, depression, weight gain, sinus infections, fatigue, back pain, headaches, severe bloating, changes in bowel movements, cramping, high blood pressure, lower back pain, decreased sex drive and so on... I went to the doctor because I had never had all of these things happen to me before. I never thought or realized it could be Mirena. My primary doctor told me my Thyroid was out of whack, and I've been on thyroid medicine for over a year now, and my levels are fine, but I keep gaining weight for no reason, and I am tired all of the time. I recently started having severe cramping and pelvic pain and went to by OBGYN.. I saw the NP and she didn't seem too concerned, and I insisted that they give me a pelvic ultrasound because I thought maybe I some ovarian cysts, as I have had in the past since I got this stupid IUD! They did the ultrasound and discovered that the IUD was quite a bit lower in the Uterus than it should be, and it was puncturing the muscle... not sure if it is a muscle or the actual uterus or what... I just had the ultrasound 3 days ago, on a Friday, and my doctor's office is suppose to be calling me today or tomorrow to let me know what's going on. I know that this IUD is coming out of my body for sure!!! I have been online now and read all the stories about other people's side effects with Mirena, and it is exactly the same for me! It is ruining my life basically! I have had it in for almost 2 years now, and I can't tell you how many times I've went to the doctor for multiple things, not realizing that it was the IUD causes all these problems!!! I would NEVER in a million years recommend Mirena IUD to anyone!!!