I had the Mirena for 5yrs & had it replaced this past April. I had loved it (no menses) but little did I know of the adverse side effects that were plaguing me. I always had some depression, but wrote it off to cyclical hormones; cystic acne that seemed to be getting worse as the years went by; heart palpitations; NO libido; anxiousness. All this seemed to happen slowly over time for me. Once I had the new one inserted, I started noticing the part in my hair was becoming thinner, like balding; developed an eczema/rash on the back of my neck at the hairline; I felt like my hay fever was non-stop & got an ear infection/sinusitis for the first time ever; then the headaches which most recently turned into a migraine with visual changes coupled with insomnia. And I ached all over like I had the flu all the time. I had no clue that the Mirena could do this until I started researching & read the PHYSICIAN insert info! I discovered that out of 21 "adverse effects" I had at least 13 of them! I was mortified - being a Ob/Gyn RN, I felt I was really misled by the manufacturer & my doctors. I could not take the headaches & insomnia any longer. A week ago, desperate & could not wait until an appt., I went into the bathroom, pulled the strings myself & removed the sucker (being a RN, I have to tell you not to do that; I was willing to take the heat should something bad happen!). Over this last week, a HUGE difference for the better. NO headaches, insomnia, body aches, skin is clearing & my mood is getting better. I actually am feeling frisky for my hubby even (who by the way will be having a vasectomy in the next couple weeks & was fully supportive of me doing this). I am so disappointed as I LOVED the no period thing, but I am not willing to risk my well-being over that!