I was on ortho-tricyclene lo for years and had no problems. I had a baby a year ago and was on a progesterone only pill due to breast feeding. I recently weaned him, and wanted to go back to the ortho. My doctor prescribed me the Ortho, and when I picked it up at the pharmacy it was the tri-sprintec. I gained weight with in the first week of taking this medication. I weighed less when my breasts where engorged with BFing!! Now my breasts are not full and I eat less and work out more and still gained weight!!! This is really discouraging because I work really hard to stay in shape and I am a petite girl, so a few pounds goes a long way on my frame. Anyway, because this is the brand name and not the generic that I want, it is a pain to request the brand name now to get it covered by insurance. I am hoping to go back to the ortho and get rid of this excess weight!!!