Prednisone is horrific! I went on it 10 months ago for autoimmune hepatitis which now I realize was a major mistake. I was to take 40 a day but only agreed to 20. Now I have very high blood pressure and am on Bystolic and Vasotec. I have gained 30 lbs and am seeing a shrink!. I have tapered the dose down to 5mg much to the docs dislike but I am depressed, anxious and a bit suicidal. Also, my lovely head of hair is at least halved and I look 7 months pregnant. Soon I'll become anorexic cuz I refuse to live any longer like this. Anyone else feel the same?