Over the past few months, I have been experiencing a variety of very bothersome symptoms and after trying to think of what medications I have recently started, the only two that I could come up with were Omeprazole and Celebrex. My symptoms are these: I have difficulty getting a "deep" breath. When I Iay down to sleep at night, I feel like I can hardly breathe. My face and neck are very swollen. I wake up in the morning with bright red cheeks and hot to the touch. I am extremely tired and depressed lately but have just thought that it was because of my increasingly bad health (chronic lower back pain and burning pain in my legs that has not "let up" for nearly 12 years now. I have recently gone on disability and this has been a very depressing experience for me after having worked and enjoyed working my entire life since I graduated high school). However, the extreme lethargy and depression I have been feeling has just been for about the past 6 to 9 months, and I started taking Omeprazole approximately November 2008. Other symptoms are swollen legs and feet....when I am out on a very hot summer day, my fingers become so swollen that by the time I get home, I cannot remove my rings from my fingers! I have begun to wake up in the morning with the most debilitating leg cramps! I have to hop out of bed and walk around to make them stop. My hip bones hurt so bad sometimes that I can hardly stand it! I have pain all over my body...it feels like it's in my bones. My joints are swollen and painful....I can hardly lift my leg and bend my knees to even get into my shower. My feet feel numb sometimes. I just ache all over! By the way.....I am a female...53 years old. Please.....has anyone else out there experienced any of these symptoms and have attributed them either to Omeprazole or Celebrex?? I feel like I'm about to lose my mind (by the way...that's another side effect I just thought of...I have a terrible time concentrating or focusing on anything! My paperwork is so backed up that soon the creditors will be after me!). But I just feel like I could lay down and sleep away the entire day and not give it a second thought. It is taking all the energy I have just to commit to typing out this posting! PLEASE HELP!! HAS ANYONE ELSE OUT THERE EXPERIENCED THE SAME SIDE EFFECTS I HAVE AND ARE BLAMING IT ON OMEPRAZOLE (OR CELEBREX?). I am on a variety of medications because of 3 failed back surgeries, however, these are the only 2 medications that I have RECENTLY begun taking. THANKS FOR ANY HELP THAT ANYONE CAN GIVE ME!!