So relieved to find that I am not alone with my symptoms. These include severe sunburn, esp. nose & vitiligo spots. Nose got very red last time I took this and I ended up with decent case of rosacea...and my nose grew larger. Cold tingling irritating feeling in my hands, feet, arms, many places. Cold water or pool feels terrible to me. I am on vacation...had to stop taking it in order to be able to enjoy myself. Before I didn't know that the med is what caused the rosacea. Now I know... I will not be taking this med again if I can avoid it. I am wondering what the long term damage is, and why there is not a warning about these symptoms on the med info sheet I rec'd. Are any of these issues causing permanent damage?