I'm glad I found this website this morning. I have been taking the generic of Zoloft (Sertraline 50mg) for 4 months now. Every night this week I have been having nightmares. I'm happy to have found a medication that works with my Generalized Anxiety/Depression--but I have started experiencing anxiety in the evenings and have insomnia also. I take it as soon as I wake up in the morning but with a new job, new hours, I have skipped on occasion this last week. I don't know if it's a side effect I should mention to my doctor?