I had Mirena inserted about 2 years ago and I'm having it removed later this week (thank goodness). I have gained 30 lbs, suffered from terrible fatigue and joint pain, mood swings, thinning hair, depression, total lack of sex drive and worst of all DEBILITATING migraines (especially after an orgasm.....I suppose that's a good reason for lack of sex drive!).
I had no problem with insertion, but was immediately aware of vaginal odor that was never there before....just an unclean sort of smell....really annoying and still persists. I miss my old periods (very normal, one week of PMS, 4 days of bleeding, then done). Now I have about 3 weeks of horrendous PMS with breast swelling, weight gain, fatigue, depression, increased appetite then I "spot" for 8-12 days! Horrible! I'll take 4 days of bleeding over 8 days of "sludge" anytime.
I hope removing it will end these issues.