I've had several bouts of Diverticulitis over the past 6 years, and this drug has worked like magic , after I was diagnosed visually during a colonoscopy. The first two rounds of 10-day therapy for two separate bouts which occurred months apart, produced no side-affects whatsoever, and the drug starting working quite soon, a perfect response. The third round however caused some stomach ache and mild dizziness for all 10 days. I realized later that I took the medicine after dinner for the first two rounds, but in the morning for the 3rd bout of diverticulitis, which occurred about a year later. Yet another year later for my 4th bout, I found that taking before bed was right for me, and even helped with my sleeping.