I am so happy I read all these posts! I have been on Loestrin 24 Fe for about 7 months now and I thought I was going crazy! After the first 3 months on it I was extremely depressed and usually I'm a very outgoing person. I called my doc and he said that usually after 3 months things will get better. So I waited and for a month things were find but then everything got so much worse then they were. I would get depressed about everything and think the craziest things which in turn made me think the craziest things. Also I always thought I was pregnant because I felt nauseous and lost my appetite and for a whole month 2 months ago my boobs were sore. This is my first bc and so I wasn't really sure what to expect. Well after reading all the posts I know I am not crazy! I am a very happy out going person but since using this pill i've been the complete opposite! As of today I am no longer using this pill! I'd rather have my horrible cramps and heavy periods then deal with feeling like I have been!