I was put on Depakote for my migraines after I had a bad experience with Topamax. It helped great with my migraines, but the weight I gained from being on it was not worth it. I have not taken it in probably 3 years, but I still cannot get my weight back to what it was before. I have always been one of those people who couldn't gain weight. Well, thanks to depakote, I am now one of those people who can't keep from gaining weight. I wish I was never introduced to the drug. I stopped taking it on my own, and my migraines are fine now. I have them sometimes but not every day.