I was prescribed Bactrim for a sinus infection. Cleared infection well but on day 2 started to feel very nauseated and VERY COLD although no fever. Strange dreams and sleeplessness. Day 3 loss of appetite and more nausea chills, (no vomiting) Day 5 wound up in Emergency room with fever, dizziness, , panic, paranoia, disorientation, pain in right side. ER took blood and my liver enzymes were elevated. They too said it was a virus...NO Way is this a virus...I have had a very bad reaction to the Bactrim. They said if it was a reaction, it would clear in a few days. I am taking milk thistle extract for liver...I had blood taken two weeks ago and liver enzymes were much lower....they had doubled on bactrim. BEWARE OF THIS Drug...(I took it when I was younger with no troubles too. Dont drink on it either (I did and this maybe why I had such a bad reaction. ) Gave me zofran for nausea. I am drinking LOTS of water to flush.