I have been on Arimidex since 2005 ,will be completing 5 yrs in 2010 .After 4 yrs ,I have started having burning sensation in my joints ,more so in my knees .I have been doing exercises prescribed very regularly ,I have added at least 7 kg in 4yrs .I have a controlled veg diet.Fatigue and body ache are the other side effects since the beginning of the drug.