I have been on Loestrin for over 2 years. I have had no bad side effects other than I no longer have a monthly cycle. Last week, I forgot to take two pills in a row, so I had to double up for two days. Since I no longer get a period, I am wondering if it is possible that I may be pregnant. My husband and I had sex on the second night that I missed a pill. On the following say is when I doubled up to get back on track. Now, a week later, I feel nauseated, tired, and hungry. I guess I have to wait and see!