I am 23 years old, and have suffered with ecxema all my life. My mother who is 55 has also suffered with ecxema all her life, and for the past couple of years, our dermatologist gives us a 40mg shot of kenalog. This shot clears our skin up immediately and lasts for a couple of weeks. It is the best thing that has ever happened to us. Neither my mother, nor myself have ever experienced any side effects. The shot is given in our hip and we have never experienced any type of indentation or discoloration. It is truly the best thing that has ever happened for our ecxema!!!