I have been on 100 mg Zoloft for 2 months now for social phobia, anxiety, and depression. Switched to it from Wellbutrin. The Wellbutrin made me feel like I was speeding my brains out. Most of the side effects have faded. My sex drive isn't like it used to be, but that's okay because my husband couldn't take much more of me the way I was! I finally get to sleep at night. I am not short and snappy with my daughter. I have a whole lot more patience. I am still working on getting out of my "safe places" and "hiding". But I am getting better each day. I actually find myself saying hello to strangers now, which I would NEVER even consider in the past! Before, my anxiety prohibited me from even having a job. Now, I think I can deal with a couple little muscle tremors vs. hiding away in my bedroom for the rest of my life! I love this medication. I was wasting my life before I started it. Now I enjoy every minute!