I'm only 19 and have terrible asthma. The doctor first put me on prednazone, then that didn't work, so he tried 50/250 advair. I've been on it for almost a year. I've had 20 lb weight gain along with terrible bloating and bowel problems, which the doc claims is "irritable bowel syndrome" but I really do think it is caused from advair after reading this! I've been trying to ween myself off it and notice that I can breathe better on my own than with it. I have a gyno appointment soon about my bloating but I do think it is from advair.